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Tresaderm Side Effects

| Updated September 26, 2017

Potential side effects of Tresaderm in dogs include skin swelling, irritation and redness. If your dog is diagnosed with a fungal or bacterial skin infection, your veterinarian might prescribe him Tresaderm, a topical medication that comes in solution form. Tresaderm also commonly treats ear and skin inflammation in canines.

Tresaderm Background

Tresaderm is made up of the anti-fungal thiabendazole, a corticosteroid called dexamethasone and a broad-spectrum antibiotic called neomycin. The dermatological solution has US Food and Drug Administration approval for canines and felines alike. The anti-fungal component of Tresaderm destroys yeast and fungi. The corticosteroid minimizes inflammation. Last but not least, the antibiotic destroys vulnerable bacteria that contribute to ear and skin troubles. Prescriptions from licensed veterinarians are required for use of Tresaderm in pets.

Possible Side Effects

If your pet is particularly sensitive to neomycin, he might experience temporary skin inflammation or redness where he was treated.

These effects typically fade within one to two days. The dexamethasone in Tresaderm sometimes causes effects such as throwing up, heightened thirst, frequent urination, weight gain and immune system suppression.

These effects occur when dogs are administered Tresaderm for excessive lengths of time and when they're administered immoderate amounts of it. Other possible side effects of the medication are shifts in behavior, diarrhea and hearing loss.

If your pet develops hearing loss, cease administering Tresaderm and notify your veterinarian without delay.

Proper Administration

Carefully abide by your veterinarian's instructions and guidelines for administering Tresaderm. If you have questions, contact your vet. This medication is not intended to be used for more than a week.


    • Make sure your veterinarian knows all of the medications your pet is taking prior to administering him Tresaderm.
    • Give your vet your dog's full medical background. Tell her about your pet's history with regard to ear troubles, allergies, stomach upset, kidney disease and liver disease. If your dog is pregnant, alert your vet.
    • Never put this medication in your dog's eyes. Never give this medication to any animal who wasn't prescribed it by a veterinarian.
    • If you notice your pet is suffering any side effects from the drug, contact your vet.


    • Tresaderm is not safe or appropriate for use in all canines.
    • It can cause potential interactions with drugs such as gentamicin, aminophylline, theophylline, other types of corticosteroids and nonsteroidal anti-inflammatory drugs. Examples of NSAIDs are carprofen, aspirin, etodolac and deracoxib.